followed by short-term liver malfunction. Very high doses lead to high calcium levels, headaches and increased pressure within the skull.
Many trials of the drug, either alone or in combination with other drugs such as interferon-alpha , are expected in the future. The biological actions of retinoids are just beginning to be understood and are quite striking.
Uracil-Ftorafur (UFT) is an oral preparation from Japan's Taiho Pharmaceutical Company that can result in consistent 5-fluorouracil blood levels. It is widely used in Japan for treating gastrointestinal and breast cancers. Studies are ongoing in the U.S. in combination with leucovorin .
